Arthrosamid® Injections

Long-lasting, proven pain relief for knee OA — without surgery

Regener8 Healthcare is revolutionising knee injections in the West Midlands.

Arthrosamid® is a simple, one-step procedure performed by Professor Mark Gillett, our in-house consultant and Chief Medical Officer for the Premier League. The procedure is done under local anaesthesia, with no need for surgery.

What is Knee Osteoarthritis?

Knee osteoarthritis (OA) is a chronic condition where the protective cartilage in the knee joint gradually wears down, leading to bone-on-bone contact. This results in stiffness, swelling, and significant pain. Over time, the degeneration of the knee joint can worsen, causing synovial pain and reduced mobility.

Unfortunately, no treatments have been able to fully halt or reverse the progression of OA, and long-lasting pain relief remains challenging. For the millions of people living with knee osteoarthritis — particularly one-third of adults over 65 — current options are largely focused on symptom management, including:

Exercise
Weight Loss
Pain Relief Medication
Viscosupplement (Hyaluronic Acid) Injections
Braces
Physiotherapy

When these approaches no longer provide sufficient relief, joint replacement surgery with an artificial prosthesis is often the final option to alleviate pain and improve quality of life.

At Regener8 Healthcare, we’re committed to offering advanced, evidence-based treatments to manage osteoarthritis effectively and support you in maintaining mobility and well-being.

Evidence Shows Synovial Pain is Linked to the Progression of Osteoarthritis

Synovitis, or synovial pain, is a common symptom experienced by individuals with knee osteoarthritis. It results from inflammation in the synovial tissue within the knee joint and is strongly associated with the intensity of pain reported by OA patients.

What is Synovial Tissue and Where is it Located?
Synovial tissue lines the interior of the knee’s joint capsule, sealing the synovial cavity. This tissue plays essential roles, including maintaining synovial fluid, supporting the nutrition of chondrocytes (cells that form cartilage), and protecting the subchondral bone (the layer beneath the cartilage)

What is Arthrosamid®?

Based on an innovative non-biodegradable hydrogel technology, Arthrosamid® is 2.5% cross-linked polyacrylamide and 97.5% water.
The medical description of Arthrosamid® is an ‘injectable polyacrylamide hydrogel’ otherwise known as ‘2.5 iPAAG’.
Approved for treatment of knee OA, Arthrosamid® is suitable, safe and effective for most patients with the condition
Arthrosamid® is the first and only approved injectable treatment that permanently combines with the knee’s synovial tissue — decreasing joint stiffness, diminishing pain, improving the function of the knee, and enhancing your quality of life.
Supported by more than two decades of research, Arthrosamid® is proven to be safe and effective — offering you long-lasting pain relief for your knee OA.
Arthrosamid® is proven to maintain a significant, long-lasting reduction in knee OA pain — even four years post-treatment
Arthrosamid® is a simple, one-step procedure performed under local anaesthesia by a qualified physician — without surgery.

How is Arthrosamid® administered?

Before treatment with Arthrosamid®, you will have a local anaesthetic to numb the area around your knee.

You should also be given antibiotics ahead of this to protect you from any potential risk of infection.

Your knee is cleaned prior to treatment. Arthrosamid® is then singularly injected into your knee’s synovial cavity. This is sometimes performed with the help of ultrasound.

The needle is then removed and a plaster is placed over the injection site.

Arthrosamid® distributes within the synovial fluid and begins to stick to and mesh with the synovial tissue.

What Is the Process?

Arthrosamid® Booking Process: Step-by-Step

Book an Initial Consultation
Schedule a consultation with Professor Mark Gillett’s Joint Team to discuss your treatment options and assess your suitability for Arthrosamid®.
Share Your Scans
If you have any recent knee scans, bring them to your consultation or send them in advance for a thorough review.
Schedule Your Injection
Once approved, book your injection appointment with Professor Gillett.
Receive Antibiotics & Instructions
You’ll be provided with antibiotics and detailed instructions on when and how to take them before your injection.
Attend Your Injection Appointment
On the day of your procedure, come to the clinic, where Professor Gillett will personally administer your Arthrosamid® injection.
Post-Injection Pain Relief
Some pain relief may be felt within hours of the injection, but maximum benefits can take up to 12 weeks. Clinic data shows that most patients experience noticeable relief within just a few weeks.

Contraindications

Arthrosamid® should not be injected:

If an active skin disease or infection is present at or near the injection site.
If the joint is infected or severely inflamed.
If the patient has previously received treatment with a different non-absorbable injectable/implant.
If the patient has received a knee alloplasty or has any foreign material in the knee.
If the patient has undergone knee arthroscopy within the last six months.
In haemophilia patients or in patients in uncontrolled anti-coagulant treatment.

Frequently Asked Questions

What are the benefits?

Arthrosamid® provides a significant reduction in your knee OA pain over a longer period – with one single treatment.

It is performed in a day that doesn’t involve the disruptive recovery period usually associated with surgery.

When should I consider Arthrosamid?

If your pain has not been improved by over-the-counter painkillers or lifestyle changes to diet and exercise, it may be time to talk to Regener8 Healthcare about Arthrosamid®.

Book an Arthrosamid Consultation

Ready to break free from the debilitating shackles of everyday knee pain? Book a consultation today to start your journey towards a pain-free life, with a bespoke treatment plan crafted by a leading specialist in the field.

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